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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jun 23, 2024 |
| Title |
Inhibition of JNK ameliorates rod photoreceptor degeneration in a mouse model of retinitis pigmentosa |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Retinitis pigmentosa (RP) is an inherited eye disease that causes progressive vision loss.To investigate the biological processes and molecular changes that occur in different cell types in the retinas in rd1 mice, a mouse model of retinitis pigmentosa, we performed single-cell RNA-seq to examine the transcriptomes of various retinal cells.
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| Overall design |
We dissected the retinas from WT and rd1 mice, and obtained retinal single-cell suspensions using Papain Dissociation System Source according to the manufacturer’s instructions.
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| Contributor(s) |
Liao C, Chen S, Yi W |
| Citation(s) |
39010325 |
| BioProject |
PRJNA1084220 |
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| Submission date |
Mar 07, 2024 |
| Last update date |
Jul 18, 2024 |
| Contact name |
Chunyan Liao |
| E-mail(s) |
cy.liao@siat.ac.cn
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| Organization name |
SIAT
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| Department |
BCBDI
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| Lab |
YuChen Lab
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| Street address |
1068 Xueyuan Avenue, Shenzhen University Town
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| City |
Shenzhen |
| ZIP/Postal code |
518000 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (4)
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| Supplementary file |
Size |
Download |
File type/resource |
| GSE261060_RAW.tar |
1.3 Gb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
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