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Series GSE262600 Query DataSets for GSE262600
Status Public on Apr 01, 2024
Title RNA-seq analysis of young adult fed 5mM tryptophan and control worms
Organism Caenorhabditis elegans
Experiment type Expression profiling by high throughput sequencing
Summary RNA-seq analysis was used to identify the gene expression changes of young adults after feeding 5mM tryptophan for 36 hours from the L4 period. Based on these sequencing data, the genes that were up-regulated or down-regulated by at least 2 times (|log2 (folding change) | ≥ 1 and padj ≤ 0.05) were analyzed. The analysis of these differentially expressed genes' pathway and gene ontology (GO) enrichment shows that the influence of different genders after feeding 5mM tryptophan is enriched to some signal pathways, including longevity、ribosome and protein degradation pathway in endoplasmic reticulum, etc.
Overall design When tryptophan was fed, mRNA profile changes for each group were generated by deep sequencing. Use Illumina Gallx
Contributor(s) zheng s
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Submission date Mar 27, 2024
Last update date Apr 01, 2024
Contact name Shanqing Zheng
Phone +8637122892869
Organization name Henan university
Street address 1 Jinming Avenue North, Longting District, School of Basic Medical Sciences, Henan University
City Kaifeng
ZIP/Postal code 475004
Country China
Platforms (1)
GPL13657 Illumina HiSeq 2000 (Caenorhabditis elegans)
Samples (6)
GSM8172209 Caenorhabditis elegans,20℃, 36 hours after L4 period, rep1
GSM8172210 Caenorhabditis elegans,20℃, 36 hours after L4 period, rep2
GSM8172211 Caenorhabditis elegans,20℃, 36 hours after L4 period, rep3
BioProject PRJNA1092623

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE262600_RAW.tar 1.5 Mb (http)(custom) TAR (of TXT)
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Raw data are available in SRA

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