|
| Status |
Public on Sep 04, 2024 |
| Title |
Mechanistic Insights and In Vivo Efficacy of Thiosemicarbazones Against Methicillin-Resistant Staphylococcus aureus |
| Organism |
Staphylococcus aureus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Thiosemicarbazone R91 targets drug-resistant S. aureus by inducing copper and oxidative stress
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| |
|
| Overall design |
A total of 6 samples were analyzed. Samples were acquired from 3 independent experiments. 3 samples were WT S. aureus treated with a vehicle control, 3 samples were WT S. aureus treated with R91.
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| |
|
| Contributor(s) |
Gaudreau A, Watson D, Heinrichs D |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 02, 2024 |
| Last update date |
Sep 04, 2024 |
| Contact name |
David Heinrichs |
| E-mail(s) |
deh@uwo.ca
|
| Organization name |
University of Western Ontario
|
| Street address |
Microbiology and Immunology, 3014 Dental Sciences Building, 1151 Richmond Street
|
| City |
London |
| State/province |
ON |
| ZIP/Postal code |
N6A5C1 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL28116 |
NextSeq 550 (Staphylococcus aureus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA1107237 |
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