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| Status |
Public on Jul 25, 2024 |
| Title |
Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To understand the molecular mechanisms underlying developmental abnormalities in Dyrk2-/- mice, we performed comprehensive whole-genome RNA sequencing of the MEFs from wild-type and Dyrk2-/- embryos
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| Overall design |
We performed gene expression profiling analysis of RNA-seq data for wild-type and Dyrk2-/- MEFs in the presence of 100 nM SAG for 24 h as well as MEFs treated with siDyrk2 or siNegative (siNeg) in the presence of 100 nM SAG for 24 h
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| Contributor(s) |
Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K |
| Citation(s) |
38968120 |
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| Submission date |
May 17, 2024 |
| Last update date |
Jul 26, 2024 |
| Contact name |
SAISHU YOSHIDA |
| E-mail(s) |
saishu@hotmail.co.jp
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| Phone |
0474721158
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| Organization name |
Toho University
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| Department |
Department of Biomolecular Science,
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| Street address |
2-2-1 Miyama, Funabashi-shi
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| City |
Chiba |
| ZIP/Postal code |
274-8510 |
| Country |
Japan |
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| Platforms (1) |
| GPL15103 |
Illumina HiSeq 1000 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA1112786 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE267749_RAW.tar |
1.3 Mb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
| Raw data are available in SRA |
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