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| Status |
Public on Jun 18, 2024 |
| Title |
Determine which gene promoter EZH2 binds to in macrophages in the state of sepsis [ChIP-seq] |
| Organism |
Mus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
In order to explore the role of EZH2 in the occurrence and development of sepsis in macrophages, we stimulated RAW264.7 cells with LPS to construct a sepsis cell model, and explored the binding site of EZH2 by co-immunoprecipitation combined with high-throughput sequencing.
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| Overall design |
We stimulated RAW264.7 cells with LPS to simulate the macrophage status in sepsis, and identified the binding site of EZH2 protein on the whole genome by chromatin immunoprecipitation (ChIP) combined with high-throughput sequencing technology.
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| Contributor(s) |
Wang Z, Wang Z |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jun 13, 2024 |
| Last update date |
Jun 18, 2024 |
| Contact name |
Ziyi Wang |
| Organization name |
Beijing Tsinghua Changgung Hospital
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| Street address |
Litang Road 168, Changping District, Beijing
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| City |
Beijing |
| ZIP/Postal code |
102218 |
| Country |
China |
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| Platforms (1) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA1123581 |
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