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| Status |
Public on Jun 20, 2024 |
| Title |
Study on the functional mechanism of NOP2 in regulating lung cancer development |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
NOP2 is a member of the NOL1/NOP2/SUN structural domain (NSUN) family and is responsible for catalyzing post-transcriptional modification of RNA via 5-methylcytosine (m5C). m5C modification dysregulation has been implicated in the pathogenesis of a variety of malignancies. Here, we investigated the expression of NOP2 in lung cancer tissues and cells and found that its expression was significantly upregulated. This is consistent with previous reports. To further investigate the mechanism by which NOP2 affects lung cancer development, RNA sequence analysis was performed. In conclusion, our study emphasizes the important role of NOP2 in lung cancer, and its promise as a potential target for lung cancer therapy.
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| Overall design |
To investigate the mechanism by which NOP2 affects lung cancer development, RNA sequence analysis was performed.
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| Contributor(s) |
Wan J |
| Citation(s) |
39013911 |
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| Submission date |
Jun 20, 2024 |
| Last update date |
Aug 09, 2024 |
| Contact name |
Junhu Wan |
| Organization name |
The First Affiliated Hospital of Zhengzhou University
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| Street address |
No. 1 Jianshe East Road
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| City |
Zhengzhou |
| ZIP/Postal code |
450052 |
| Country |
China |
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| Platforms (1) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA1126124 |
