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| Status |
Public on Jul 07, 2024 |
| Title |
Biochemical characterization, biosynthesis mechanism, and functional evaluation of selenium-enriched Aspergillus oryzae A02 |
| Organism |
Aspergillus oryzae |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The synthesis mechanisms and function evaluation of selenium(Se)-enriched microorganism remain relatively unexplored. We here report the Se biotransformation by A. oryzae A02. Comparative RNA-Seq analysis revealed the upregulation of functional genes implicated in selenium transformation, activating multiple potential pathways for selenium reduction. The assimilatory and dissimilatory reductions of Se oxyanions engaged numerous parallel and interconnected pathways, manifesting a harmonious equilibrium in overall Se biotransformation in A. oryzae A02.
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| Overall design |
To investigate the effect of Se on the transcriptional profiles of Aspergillus oryzae. A. oryzae was treated or untreated with Se for 12h, 24h and 48h and then comparative gene expression profiling analysis was performed.
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| Web link |
https://linkinghub.elsevier.com/retrieve/pii/S0141-8130(24)04519-7
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| Contributor(s) |
Gao L, Li J |
| Citation(s) |
38977051 |
| BioProject |
PRJNA1127324 |
| |
| Submission date |
Jun 26, 2024 |
| Last update date |
Jul 15, 2024 |
| Contact name |
Jinyang Li |
| E-mail(s) |
lijy@tib.cas.cn
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| Organization name |
Chinese Academy of Sciences
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| Street address |
No. 32, Xiqi Road, Tianjin Airport Economic Park
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| City |
Tianjin |
| ZIP/Postal code |
300308 |
| Country |
China |
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| Platforms (1) |
| GPL34650 |
BGISEQ-500 (Aspergillus oryzae) |
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| Samples (18)
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| GSM8353853 |
Replication 1 of Control for 12h (Con12) |
| GSM8353854 |
Replication 2 of Control for 12h (Con12) |
| GSM8353855 |
Replication 3 of Control for 12h (Con12) |
| GSM8353856 |
Replication 1 of Control for 24h (Con24) |
| GSM8353857 |
Replication 2 of Control for 24h (Con24) |
| GSM8353858 |
Replication 3 of Control for 24h (Con24) |
| GSM8353859 |
Replication 1 of Control for 48h (Con48) |
| GSM8353860 |
Replication 2 of Control for 48h (Con48) |
| GSM8353861 |
Replication 3 of Control for 48h (Con48) |
| GSM8353862 |
Replication 1 of Se treatment for 12h (Se12) |
| GSM8353863 |
Replication 2 of Se treatment for 12h (Se12) |
| GSM8353864 |
Replication 3 of Se treatment for 12h (Se12) |
| GSM8353865 |
Replication 1 of Se treatment for 24h (Se24) |
| GSM8353866 |
Replication 2 of Se treatment for 24h (Se24) |
| GSM8353867 |
Replication 3 of Se treatment for 24h (Se24) |
| GSM8353868 |
Replication 1 of Se treatment for 48h (Se48) |
| GSM8353869 |
Replication 2 of Se treatment for 48h (Se48) |
| GSM8353870 |
Replication 3 of Se treatment for 48h (Se48) |
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