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| Status |
Public on Jun 01, 2006 |
| Title |
GAP aflR- vs WT timecourse |
| Platform organism |
Aspergillus flavus |
| Sample organism |
Aspergillus parasiticus |
| Experiment type |
Expression profiling by array
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| Summary |
The carcinogen aflatoxin is synthesized by a cluster of genes that are regulated by the transcriptional factor, AflR. Most, but not all of these genes, have a consensus binding site for AflR in their 5’ untranslated region. Because aflR resides within the biosynthetic cluster, is has been suggested that it regulates only genes within the cluster. The objective of this study was to identify those genes transcriptionally regulated by AflR and to determine if any of those genes reside outside the aflatoxin biosynthetic cluster. To address this objective, we employed a cDNA microarray of 5,002 genes from Aspergillus flavus to monitor the expression of genes in a wild type and an aflR deletion strain of A. parasiticus.
Keywords = aspergillus
Keywords = aflatoxin
Keywords = regulation
Keywords = secondary metabolism
Keywords: time-course
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| Contributor(s) |
Price MS, Yu J, Nierman WC, Kim S, Pritchard B, Bhatnagar D, Cleveland TE, Payne GA |
| Citation(s) |
16448506 |
| Submission date |
May 25, 2005 |
| Last update date |
Mar 16, 2012 |
| Contact name |
Michael S Price |
| E-mail(s) |
msprice2@liberty.edu
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| Phone |
434-592-7277
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| Organization name |
Liberty University
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| Department |
Biology & Chemistry
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| Street address |
1971 University Blvd.
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| City |
Lynchburg |
| State/province |
VA |
| ZIP/Postal code |
24515 |
| Country |
USA |
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| Platforms (1) |
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| Samples (12)
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| GSM52402 |
WT vs aflR mutant timecourse slide 1 |
| GSM52403 |
WT vs aflR mutant timecourse slide 2 |
| GSM52404 |
WT vs aflR mutant timecourse slide 3 |
| GSM52405 |
WT vs aflR mutant timecourse slide 4 |
| GSM52406 |
WT vs aflR mutant timecourse slide 5 |
| GSM52407 |
WT vs aflR mutant timecourse slide 6 |
| GSM52408 |
WT vs aflR mutant timecourse slide 7 |
| GSM52409 |
WT vs aflR mutant timecourse slide 8 |
| GSM52410 |
WT vs aflR mutant timecourse slide 9 |
| GSM52411 |
WT vs aflR mutant timecourse slide 10 |
| GSM52412 |
WT vs aflR mutant timecourse slide 11 |
| GSM52413 |
WT vs aflR mutant timecourse slide 12 |
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| Relations |
| BioProject |
PRJNA92361 |
| Supplementary data files not provided |
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