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| Status |
Public on Apr 22, 2011 |
| Title |
Integrated miRNA-mRNA-analysis of human monocyte derived macrophages upon Mycobacterium avium subsp. hominissuis infection |
| Platform organisms |
Homo sapiens; Mus musculus; Rattus norvegicus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; human gammaherpesvirus 4; JC polyomavirus; Human immunodeficiency virus 1; Murid gammaherpesvirus 4; Human gammaherpesvirus 8; Betapolyomavirus hominis; Betapolyomavirus macacae |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
Expression profiling by array
|
| Summary |
The host response to mycobacterial infections was studied after infection of macrophages derived from primary human monocytes. mRNA and miRNA expression studies were performed to identify key regulators of immune defence and their targets.
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| Overall design |
Experimental samples were taken 6h, 24h and 48h after infection of monocyte derived macrophages with two mycobacterial strains (MAH10091 and MAH104)
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| Contributor(s) |
Sharbati J, Lewin A, Kutz-Lohroff B, Kamal E, Einspanier R, Sharbati S |
| Citation(s) |
21629653 |
| |
| Submission date |
Feb 07, 2011 |
| Last update date |
Jan 13, 2016 |
| Contact name |
Soroush Sharbati |
| E-mail(s) |
sharbati@zedat.fu-berlin.de
|
| Organization name |
Freie Universitaet Berlin
|
| Department |
Institute of Veterinary Biochemistry
|
| Street address |
Oertzenweg 19b
|
| City |
Berlin |
| ZIP/Postal code |
14163 |
| Country |
Germany |
| |
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| Platforms (2) |
| GPL7722 |
miRCURY LNA microRNA Array, v.10.0 - hsa, mmu & rno |
| GPL10128 |
Miltenyi PIQOR (TM) Human Immunology Microarray, antisense |
|
| Samples (12)
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| Relations |
| BioProject |
PRJNA137437 |
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