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| Status |
Public on Jul 10, 2024 |
| Title |
Comparative physiologycal and transcriptome analysis of Candida auris and Candida albicans to exogenous homoserine-lactone |
| Organisms |
Candida albicans; [Candida] auris |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Interaction between Candida species and Pseudomonas aeruginosa is frequnetly observed in clinical practice. The 3-oxo-C12 homoserine-lactone (3OC12HSL) is a well-known P. aeruginosa quorum-sensing molecule, of which effect is not fully understand for different Candida species. Therefore, we examined the effect of 3OC12HSL to C. albicans and C. auris virulence, biofilm formation and transcriptome in comparative manner.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data of hooserin lacton treated and untreated Candida auris and Candida albicans cells.
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| Contributor(s) |
Kovács F, Tóth Z, Balla N, Ragyák Á, Bozó A, Balázsi D, Forgács L, Harmath A, Nemes D, Bácskay I, Majoros L, Jakab Á, Kovács R |
| Citation missing |
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| |
| Submission date |
Jul 05, 2024 |
| Last update date |
Jul 10, 2024 |
| Contact name |
Agnes Jakab |
| E-mail(s) |
jakab.agnes@med.unideb.hu
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| Organization name |
University of Debrecen
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| Street address |
Nagyerdei krt 98.
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| City |
Debrecen |
| ZIP/Postal code |
4032 |
| Country |
Hungary |
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| Platforms (2) |
| GPL22403 |
Illumina NextSeq 500 (Candida albicans) |
| GPL24811 |
Illumina NextSeq 500 ([Candida] auris) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA1132143 |
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