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| Status |
Public on Jul 31, 2024 |
| Title |
TetR-like regulator BP1026B_II1561 controls aromatic amino acid biosynthesis and intracellular pathogenesis in Burkholderia pseudomallei [RNA-seq] |
| Organism |
Burkholderia pseudomallei |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We identified BP1026b_II1561 to be an important transcriptional regulator controling late stages of intracellular infection. RNA-seq analysis was performed to further investigate the regulatory network of II1561 regulation. ChIP-seq was also performed under the same conditions.
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| Overall design |
Differential gene expression and ChIP seq was performed comparing a strain expressing II1561 to an empty vector control.
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| Contributor(s) |
McMillan IA, Norris MH, Hoang TT |
| Citation(s) |
39211319 |
| |
| Submission date |
Jul 30, 2024 |
| Last update date |
Sep 30, 2024 |
| Contact name |
Ian A McMillan |
| Organization name |
University of Hawaii
|
| Street address |
1800 East-west road
|
| City |
Honolulu |
| State/province |
HI |
| ZIP/Postal code |
96822 |
| Country |
USA |
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| Platforms (1) |
| GPL32930 |
Illumina HiSeq 2500 (Burkholderia pseudomallei) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA1141966 |
