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| Status |
Public on Oct 10, 2024 |
| Title |
Gene expression profile of different cell types in the tumor microenvironment of MOC1 tumors treated with Smyd3 anti-sense oligonucleotides (ASOs). |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We used scRNA-seq to assess the differential effect of Smyd3 ASOs on the transcriptomic profile of different cell types in the TME of MOC1 tumors.
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| Overall design |
MOC1 tumors were implanted in the flank of C57BL/6 mice were treated with control (n=3) or Smyd3 ASOs (n=3) for 18 days. Tumors were surgically resected, digested into single-cell suspensions and scRNA-seq was conducted.
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| Contributor(s) |
Saloura V, Lobanov A, Abdelmaksoud A |
| Citation(s) |
39310755 |
| |
| Submission date |
Jul 30, 2024 |
| Last update date |
Oct 11, 2024 |
| Contact name |
Vassiliki Saloura |
| E-mail(s) |
vassiliki.saloura@nih.gov
|
| Phone |
2156099664
|
| Organization name |
NCI
|
| Department |
TGMB
|
| Lab |
Saloura
|
| Street address |
11705 STONEWOOD LN
|
| City |
ROCKVILLE |
| State/province |
MARYLAND |
| ZIP/Postal code |
20852 |
| Country |
USA |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA1142030 |
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