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| Status |
Public on Dec 02, 2012 |
| Title |
Transcriptional profile of ΔcalA and ΔcrzA Aspergillus fumigatus mutants during mammal infection |
| Platform organism |
Aspergillus fumigatus Af293 |
| Sample organism |
Aspergillus fumigatus |
| Experiment type |
Expression profiling by array
|
| Summary |
Aspergillus fumigatus mutant strains were collected from bronchoalveolar lavage fluids (BALFs) during acute mouse infection (4 and 12 hours).
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| Overall design |
Transcriptional analysis were conducted by comparison of each mutant with the wild type strain (CEA17) in a dye swap experiment. Besides, we performed the transcriptional profile of akuB(KU80) mutant compared to CEA17 wild type strain. All the strains were recovered from bronchoalveolar lavage fluid from CD1 mice infected with 10e8 spores for 4 and 12 hours.
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| Contributor(s) |
Soriani FM, Cairns CT, Loss O, Bignell E, Goldman GH |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Feb 21, 2011 |
| Last update date |
Dec 02, 2012 |
| Contact name |
Gustavo Henrique Goldman |
| E-mail(s) |
ggoldman@usp.br
|
| Phone |
55-016-36024280
|
| Fax |
55-016-36024280
|
| Organization name |
Faculty of Pharmaceutical Sciences of Ribeirao Preto
|
| Department |
Departament of Pharmaceutical Sciences
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| Lab |
Laboratory of Molecular Biology
|
| Street address |
Avenida do Café, s/n
|
| City |
Ribeirao Preto |
| State/province |
Sao Paulo |
| ZIP/Postal code |
14040-903 |
| Country |
Brazil |
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| Platforms (1) |
| GPL10341 |
JCVI Aspergillus fumigatus AF293 29.9K amplicon array |
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| Samples (6)
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| GSM678114 |
Control wild type vs control akuB(KU80) strains time point 4 hours |
| GSM678115 |
Control wild type vs control akuB(KU80) strains time point 12 hours |
| GSM678116 |
Control wild type vs control ΔcalA strains time point 4 hours |
| GSM678117 |
Control wild type vs control ΔcalA strains time point 12 hours |
| GSM678118 |
Control wild type vs control ΔcrzA strains time point 4 hours |
| GSM678119 |
Control wild type vs control ΔcrzA strains time point 12 hours |
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| Relations |
| BioProject |
PRJNA137217 |
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