|
| Status |
Public on Jul 01, 2005 |
| Title |
Gene expression in the Gli3Xt/Xt Vs wildtype developing limb |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We used microarray technology to investigate the transcriptional consequences of loss of Gli3
from the anterior mesenchyme of the developing mouse limb bud at both E11.5 and E12.5.
Comparisons were made between RNA derived from the anterior margin of Gli3Xt/Xt limb buds
and that derived from wild type littermates
Keywords: genetic modification
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| Overall design |
The experiment contains a series of pairwise comparisons between staged mutant Gli3(Xt/Xt) and WT anterior portions of limb bud at 11.5dpc and 12.5dpc. Forelimbs and hindlimbs were studied independently given the developmental delay between limb buds.
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| Contributor(s) |
McGlinn E, Lammerts van Bueren K, Fiorenza S, Mo R, Po AM, Forrest AR, Soares MB, de Fatima Bonaldo M, Grimmond SM, Hui C, Wainwright B, Wicking C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 13, 2005 |
| Last update date |
Mar 16, 2012 |
| Contact name |
Sean M Grimmond |
| E-mail(s) |
s.grimmond@imb.uq.edu.au
|
| Phone |
61 7 3346 2057
|
| Fax |
61 7 3346 2101
|
| Organization name |
Institute of Molecular Bioscience
|
| Street address |
IMB, Uni of Qld
|
| City |
St Lucia |
| State/province |
QLD |
| ZIP/Postal code |
4027 |
| Country |
Australia |
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| Platforms (2) |
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| Samples (16)
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| GSM60868 |
11.5dpc Gli3Xt/Xt Vs wild type forelimb |
| GSM60869 |
11.5dpc Gli3Xt/Xt Vs wild type forelimb b |
| GSM60870 |
11.5dpc Gli3Xt/Xt Vs wild type hindlimb |
| GSM60871 |
11.5dpc Gli3Xt/Xt Vs wild type hindlimb b |
| GSM60872 |
12.5dpc Gli3Xt/Xt Vs wild type forelimb |
| GSM60873 |
12.5dpc Gli3Xt/Xt Vs wild type forelimb b |
| GSM60874 |
12.5dpc Gli3Xt/Xt Vs wild type hindlimb b |
| GSM60875 |
12.5dpc Gli3Xt/Xt Vs wild type hindlimb |
| GSM60876 |
11.5dpc Gli3Xt/Xt Vs wild type forelimb NIA |
| GSM60877 |
11.5dpc Gli3Xt/Xt Vs wild type forelimb NIA B |
| GSM60878 |
11.5dpc Gli3Xt/Xt Vs wild type hindlimb NIA |
| GSM60879 |
12.5dpc Gli3Xt/Xt Vs wild type hindlimb NIA |
| GSM60880 |
11.5dpc Gli3Xt/Xt Vs wild type hindlimb NIA B |
| GSM60881 |
12.5dpc Gli3Xt/Xt Vs wild type hindlimb B |
| GSM60882 |
12.5dpc Gli3Xt/Xt Vs wild type forelimb NIA |
| GSM60883 |
12.5dpc Gli3Xt/Xt Vs wild type forelimb NIA B |
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| Relations |
| BioProject |
PRJNA92405 |
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