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Status |
Public on Jul 19, 2011 |
Title |
Gene expression data from human CD34+ cord blood cells infected with MIGR1, MIGR1-AML1-ETO or MIGR1-AML1-ETO∆NHR1 |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Compare the gene expression profile among human CD34+ cord blood cells infected with MIGR1, MIGR1-AML1-ETO or MIGR1-AML1-ETO∆NHR1 AML1-ETO promotes the self-renewal of human hematopoietic stem/progenitor cells (HSPCs). We found deletion of NHR1 domain abrogates AML1-ETO induced expasion of HSPCs.
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Overall design |
GFP+CD34+ human cord blood cells were sorted by FACS 72 hours after the infection for RNA extraction and hybridyzation for Affymetrix microarrays.
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Contributor(s) |
Wang L, Nimer SD |
Citation(s) |
21764752 |
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Submission date |
Apr 01, 2011 |
Last update date |
Mar 25, 2019 |
Contact name |
Jeffrey Zhao |
Organization name |
Memorial Sloan Kettering Cancer Center
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Department |
Genomics Core
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Street address |
1275 York Avenue
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City |
New York |
State/province |
NY |
ZIP/Postal code |
10065 |
Country |
USA |
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Platforms (1) |
GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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Samples (9)
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Relations |
BioProject |
PRJNA139335 |