|
| Status |
Public on Nov 18, 2011 |
| Title |
Characterization of expression changes in qin by tiling array |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by genome tiling array
|
| Summary |
Qin, a novel protein comprising amino-terminal E3 ligase and five carboxy terminal Tudor domains, silences transposons and ensures genome stability in the Drosophila germline by promoting antisene piRNA amplification via Aubergine:Ago3 Ping-Pong and preventing futile Aubergine:Aubergine interactions.
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| |
|
| Overall design |
Extract total ovary RNAs, and using tiling array to test transposon as well as gene expression in wild-type and qin mutant flies. Three biological replicates are used.
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| |
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| Contributor(s) |
Zhang Z, Zamore P, Weng Z, Theurkauf W |
| Citation(s) |
22099305 |
| |
| Submission date |
Jun 17, 2011 |
| Last update date |
Jul 08, 2015 |
| Contact name |
Zhao Zhang |
| E-mail(s) |
zhao.zhang@umassmed.edu
|
| Phone |
508-918-9608
|
| Organization name |
UMass Medical School
|
| Department |
BMP
|
| Lab |
Zamore/Theurkauf
|
| Street address |
LRB-870N, 364 Plantation Street
|
| City |
Worcester |
| State/province |
MA |
| ZIP/Postal code |
01605 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL6629 |
[DM_tiling2_MR] Affymetrix Drosophila Tiling 2.0R Array |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA144029 |
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