|
| Status |
Public on Jul 30, 2005 |
| Title |
Prediction of drug sensitivity |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Tumor cell lines and drug-resistant counterparts. These data support the publication Gyorffy et al, Oncogene 2005 (July), Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.
We contrasted the expression profiles of 13 different human tumor cell lines of gastric (EPG85-257), pancreatic (EPP85-181), colon (HT29) and breast (MCF7 and MDA-MB-231) origin and their counterparts resistant to the topoisomerase inhibitors daunorubicin, doxorubicin or mitoxantrone. We interrogated cDNA arrays with 43 000 cDNA clones ( approximately 30 000 unique genes) to study the expression pattern of these cell lines.
A cell type comparison design experiment design type compares cells of different type for example different cell lines.
Keywords: cell_type_comparison_design
|
| |
|
| Overall design |
Using regression correlation
|
| |
|
| Contributor(s) |
Garber M |
| Citation(s) |
16044152 |
| |
| Submission date |
Jul 29, 2005 |
| Last update date |
Sep 19, 2012 |
| Organization |
Stanford Microarray Database (SMD) |
| E-mail(s) |
array@genome.stanford.edu
|
| Phone |
650-498-6012
|
| URL |
http://genome-www5.stanford.edu/
|
| Department |
Stanford University, School of Medicine
|
| Street address |
300 Pasteur Drive
|
| City |
Stanford |
| State/province |
CA |
| ZIP/Postal code |
94305 |
| Country |
USA |
| |
|
| Platforms (2) |
|
| Samples (13)
|
|
| Relations |
| BioProject |
PRJNA93043 |
Less...
More...