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Status |
Public on Nov 22, 2011 |
Title |
Colorectal cancers with microsatellite instability display unique miRNA profiles |
Organism |
Homo sapiens |
Experiment type |
Non-coding RNA profiling by array
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Summary |
Analysis of microRNA expression of tumoral and non-tumoral colonic tissues. The aim of this study was to analyze the global miRNA signatures in various groups of well-characterized CRCs based on the presence of microsatellite instability (MSI).
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Overall design |
Total RNA from formalin-fixed paraffin-embedded tissue blocks from 4 different groups (normal colonic mucosa, Lynch syndrome tumors, sporadic MSI tumors and MSS tumors) was isolated using the RecoverAll Total Nucleic Acid Isolation Kit (Ambion) according to manufacturer instructions. MiRNA expression profiles were analyzed using miRNA microarray platform.
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Contributor(s) |
Balaguer F, Moreira L, Lozano JJ, Link A, Ramirez G, Shen Y, Cuatrecasas M, Arnold M, Meltzer SJ, Syngal S, Stoffel E, Jover R, Llor X, Castells A, Boland CR, Gironella M, Goel A |
Citation(s) |
21844009 |
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Submission date |
Jul 06, 2011 |
Last update date |
Feb 18, 2019 |
Contact name |
Juanjo Lozano |
E-mail(s) |
juanjo.lozano@ciberehd.org
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Organization name |
CIBEREHD
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Department |
Plataforma de Bioinformatica
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Street address |
C/ Rosselló 153
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City |
Barcelona |
ZIP/Postal code |
08036 |
Country |
Spain |
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Platforms (1) |
GPL8179 |
Illumina Human v2 MicroRNA expression beadchip |
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Samples (74)
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Relations |
BioProject |
PRJNA143541 |
Supplementary file |
Size |
Download |
File type/resource |
GSE30454_RAW.tar |
70.0 Kb |
(http)(custom) |
TAR |
GSE30454_non-normalized_data.txt.gz |
455.2 Kb |
(ftp)(http) |
TXT |
Processed data included within Sample table |
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