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| Status |
Public on Jun 26, 2013 |
| Title |
Molecular Signature of Pregnancy Associated Breast Cancer (PABC) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Malignant epithelia and tumor-associated stroma of PABC and Non-PABC were isolated by laser capture microdissection and gene expression profiled. Additionally, normal breast epithelia and stroma adjacent to the two tumor types were profiled.
Lastly, subsets of previously identified E- and P-regulated genes were defined in all tissues.
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| Overall design |
Breast cancers have been obtained from women whose tumors arose while they were pregnant or within 1 year of delivery and from age-matched controls who had never been pregnant. Malignant epithelial cells were separated by laser capture microdissection (LCM) of frozen sections. RNA was isolated and analyzed by expression profiling using Affymetrix U133 2plus Human Gene Chips
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| Contributor(s) |
Harvell D, Kim J |
| Citation(s) |
23479404 |
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| Submission date |
Aug 03, 2011 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Jihye Kim |
| E-mail(s) |
kim.jihey@gmail.com
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| Phone |
7209755448
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| Organization name |
Cleveland Clinic
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| Department |
Quantitative Health Sciences
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| Street address |
9500 Euclid Ave.
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| City |
Cleveland |
| State/province |
Ohio |
| ZIP/Postal code |
44195 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (33)
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| GSM773284 |
BC07_20, PABC, ER neg, Epithelial, Epithelial |
| GSM773285 |
BC07_20, PABC, ER neg, Stroma, Stroma |
| GSM773286 |
BC07_37, NonPABC, ER neg, Epithelial, Normal Epithelial |
| GSM773287 |
BC06-25, NonPABC, ER pos, Epithelial, DCIS Epithelial |
| GSM773288 |
BC06-25, NonPABC, ER pos, Stroma, DCIS Stroma |
| GSM773289 |
BC07_37, NonPABC, ER neg, Stroma, Stroma |
| GSM773290 |
BC08-72, PABC, ER pos, Epithelial, Epithelial |
| GSM773291 |
BC06_57, NonPABC, ER pos, Epithelial, Epithelial |
| GSM773292 |
BC08-72, PABC, ER pos, Stroma, Stroma |
| GSM773293 |
BC06_57, NonPABC, ER pos, Stroma, Stroma |
| GSM773294 |
BC08-72, PABC, ER pos, Stroma, Normal Stroma (07) |
| GSM773295 |
BC06_52, PABC, ER pos, Epithelial, Epithelial |
| GSM773296 |
BC08-72, PABC, ER pos, Stroma, Normal Stroma (08) |
| GSM773297 |
BC06_52, PABC, ER pos, Stroma, Stroma |
| GSM773298 |
BC08-72, PABC, ER pos, Epithelial, Normal Epithelial |
| GSM773299 |
BC06-21, NonPABC, ER pos, Epithelial, Normal Epithelial |
| GSM773300 |
BC07_29, PABC, ER neg, Epithelial, Epithelial |
| GSM773301 |
BC07_29, PABC, ER neg, Stroma, Stroma |
| GSM773302 |
BC08-55, PABC, ER pos, Epithelial, Epithelial |
| GSM773303 |
BC08-55, PABC, ER pos, Stroma, Stroma |
| GSM773304 |
BC07_47, PABC, ER pos, Epithelial, Normal Epithelial |
| GSM773305 |
BC08-49, NonPABC, ER pos, Epithelial, Epithelial |
| GSM773306 |
BC08-49, NonPABC, ER pos, Stroma, Stroma |
| GSM773307 |
BC07_47, PABC, ER pos, Stroma, Stroma |
| GSM773308 |
BC08-24, NonPABC, ER neg, Epithelial, Epithelial |
| GSM773309 |
BC07_19, NonPABC, ER neg, Epithelial, Normal Epithelial |
| GSM773310 |
BC08-24, NonPABC, ER neg, Stroma, Stroma |
| GSM773311 |
BC08-103, PABC, ER neg, Epithelial, Epithelial |
| GSM773312 |
BC07_19, NonPABC, ER neg, Stroma, Stroma |
| GSM773313 |
BC08-103, PABC, ER neg, Stroma, Normal Stroma (19) |
| GSM773314 |
BC08-103, PABC, ER neg, Epithelial, Normal Epithelial |
| GSM773315 |
BC08-103, PABC, ER neg, Stroma, Normal Stroma (21) |
| GSM773316 |
BC08-103, PABC, ER neg, Stroma, Stroma |
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| Relations |
| BioProject |
PRJNA144751 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE31192_RAW.tar |
149.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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