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| Status |
Public on Jul 31, 2014 |
| Title |
Transcriptome profiling of Hansenula polymorpha in response to sulfur starvation and cadmium stress |
| Organism |
Ogataea angusta |
| Experiment type |
Expression profiling by array
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| Summary |
Transcriptome profiling analysis of the Hansenula polymorpha MET4 gene deletion strain have been carried out to obtain comprehensive information on the HpMet4p-mediated regulatory networks in association with the cadmium (Cd) detoxification and sulfur regulation in H. polymorpha.
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| Overall design |
Total RNA samples were collected from H. polymorpha wild type, and HpMET4 deletion strain, under sulfur starvation or Cd (0.6 mM) stress conditions. The differential fluorescence intensities of each RNA sample were measured after labeling with Cy3 or Cy5. For all analyses, we performed dye swapping experiments to avoid dye bias. Thus, four intensity values were generated for each ORF and averaged for analysis.
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| Contributor(s) |
Sohn M, Ubiyvovk VM, Oh D, Kwon O, Lee S, Sibirny AA, Rhee S, Kang H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Aug 03, 2011 |
| Last update date |
Jul 31, 2014 |
| Contact name |
Min Jeong Sohn |
| E-mail(s) |
sohnmj@kaist.ac.kr
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| Phone |
+82-42-860-4454
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| Fax |
+82-42-860-4594
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| Organization name |
Korea Research Institute of Bioscience and Biotechnology
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| Department |
Protein therapeutics research center
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| Street address |
52 Eoeun-dong, Yuseong-gu
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| City |
Daejeon |
| ZIP/Postal code |
305-333 |
| Country |
South Korea |
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| Platforms (1) |
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| Samples (15)
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| GSM606076 |
Hansenula polymorpha DL1-L sulfur starvation, rep1 |
| GSM608856 |
Hansenula polymorpha DL1-L sulfur starvation, rep2 |
| GSM608857 |
Hansenula polymorpha DL1-L sulfur starvation, rep3 |
| GSM608858 |
Hansenula polymorpha DL1-L sulfur starvation, rep4 |
| GSM608859 |
Hansenula polymorpha Hpmet4 sulfur starvation, rep1 |
| GSM608882 |
Hansenula polymorpha Hpmet4 sulfur starvation, rep2 |
| GSM608883 |
Hansenula polymorpha Hpmet4 sulfur starvation, rep3 |
| GSM608884 |
Hansenula polymorpha Hpmet4 sulfur starvation, rep4 |
| GSM614390 |
Hansenula polymorpha DL1-L Cd, rep1 |
| GSM614477 |
Hansenula polymorpha DL1-L Cd, rep2 |
| GSM614478 |
Hansenula polymorpha DL1-L Cd, rep3 |
| GSM614479 |
Hansenula polymorpha DL1-L Cd, rep4 |
| GSM614480 |
Hansenula polymorpha Hpmet4 Cd, rep1 |
| GSM614481 |
Hansenula polymorpha Hpmet4 Cd, rep2 |
| GSM659009 |
Hansenula polymorpha Hpmet4 Cd, rep3 |
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| Relations |
| BioProject |
PRJNA144747 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE31197_RAW.tar |
17.9 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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