|
| Status |
Public on Dec 08, 2011 |
| Title |
MicroRNA expression in chronic rhinosinusitis |
| Platform organisms |
Homo sapiens; Mus musculus; Rattus norvegicus; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Betapolyomavirus hominis; Betapolyomavirus macacae |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
Increasing evidence suggests that CRS is a heterogeneous group of sinus disorders involving overlapping but distinct disease entities.The factors leading to different CRS phenotypes remain enigmatic. The role of miRNAs in the regulation of immunological and inflammatory processes is beginning to emerge.Thus, we examined microRNAs expression profiles in eosinophilic CRSwNP adn CRSsNP. Compared with controls, 31 differentially expressed miRNAs (30 downregulated and 1 upregulated miRNAs) in eosinophilic CRSwNP and 4 differentially expressed miRNAs (2 downregulated and 2 upregulated miRNAs) in CRSsNP were indentified. Real time RT-PCR was subsequently performed to verify the miRNA microarray result.
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| |
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| Overall design |
Examination of miRNAs expression in eosinophilic CRSwNP and CRSsNP
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| |
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| Contributor(s) |
Zhang X |
| Citation(s) |
22071331 |
| |
| Submission date |
Sep 22, 2011 |
| Last update date |
Mar 23, 2012 |
| Contact name |
zhang xinhao |
| E-mail(s) |
azhang1@163.com
|
| Phone |
008602783663334
|
| Fax |
008602783663334
|
| Organization name |
Tongji Hospital
|
| Street address |
1095 Jiefang Avenue
|
| City |
Wuhan |
| ZIP/Postal code |
430030 |
| Country |
China |
| |
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| Platforms (1) |
| GPL7724 |
miRCURY LNA microRNA Array, v. 9.2, all organisms |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA146373 |
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