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| Status |
Public on Jan 01, 2012 |
| Title |
Expression data from docetaxel-resistant prostate cancer cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Docetaxel-based chemotherapy is the standard first-line therapy in metastatic castration-resistant prostate cancer. However, most patients eventually develop resistance to this treatment.
The aim of the study was to identify key molecular genes and networks associated with docetaxel resistance in 2 models of docetaxel-resistant castration-resistant prostate cancer cell lines.
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| |
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| Overall design |
DU-145 and PC-3 cells were converted to docetaxel-resistant cells, DU-145R and PC-3R, respectively. Whole-genome arrays were used to compare global gene expression between these 4 cell lines. Arrays were performed by triplicate for each cell line.
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| |
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| Contributor(s) |
Marín-Aguilera M, Kalko SG, Mellado B |
| Citation(s) |
22027694 |
| |
| Submission date |
Nov 03, 2011 |
| Last update date |
Mar 12, 2020 |
| Contact name |
Mercedes Marín-Aguilera |
| E-mail(s) |
mmarin1@clinic.ub.es
|
| Organization name |
Fundació Clínic per a la Recerca Biomèdica
|
| Street address |
Villarroel 170
|
| City |
Barcelona |
| ZIP/Postal code |
08036 |
| Country |
Spain |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (12)
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| Relations |
| Affiliated with |
GSE67157 |
| BioProject |
PRJNA148679 |
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