|
| Status |
Public on Dec 25, 2012 |
| Title |
Microarray Analysis of Toxicogenomic Effects of Triclosan on Mycobacterium bovis BCG |
| Organism |
Mycobacterium tuberculosis variant bovis BCG |
| Experiment type |
Expression profiling by array
|
| Summary |
Global gene expression analysis of Mycobacterium bovis BCG following Triclosan treatment using Affymetrix GeneChip arrays. Results from this study provide insight into the molecular mechanisms underlying the cellular response of Mycobacterium bovis BCG to Triclosan
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| |
|
| Overall design |
We conducted three independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of triclosan. Fold change was calculated as a ration between the signal averages of three untreated (control) and three triclosan-treated (experimental) cultures for 0, 10 and 60min exposures.
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| |
|
| Contributor(s) |
San Miguel C, Mulinti P, Jang H, Toghrol F |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 18, 2011 |
| Last update date |
Dec 25, 2012 |
| Contact name |
Prashanthi Mulinti |
| E-mail(s) |
Mulinti.Prashanthi@epa.gov
|
| Phone |
410-305-2860
|
| Fax |
410-305-3091
|
| Organization name |
USEPA
|
| Department |
OPP/BEAD
|
| Lab |
MARL
|
| Street address |
701 Mapes Road
|
| City |
Ft. Meade |
| State/province |
MD |
| ZIP/Postal code |
20755 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL7549 |
Affymetrix Mycobacterium bovis BCG GeneChip Array |
|
| Samples (9)
|
| GSM836057 |
Mycobacterium bovis BCG_no treatment_0min_replicate1 |
| GSM836058 |
Mycobacterium bovis BCG_no treatment_0min_replicate2 |
| GSM836059 |
Mycobacterium bovis BCG_no treatment_0min_replicate3 |
| GSM836060 |
Mycobacterium bovis BCG_Triclosan_10min_replicate1 |
| GSM836061 |
Mycobacterium bovis BCG_Triclosan_10min_replicate2 |
| GSM836062 |
Mycobacterium bovis BCG_Triclosan_10min_replicate3 |
| GSM836063 |
Mycobacterium bovis BCG_Triclosan_60min_replicate1 |
| GSM836064 |
Mycobacterium bovis BCG_Triclosan_60min_replicate2 |
| GSM836065 |
Mycobacterium bovis BCG_Triclosan_60min_replicate3 |
|
| Relations |
| BioProject |
PRJNA148115 |
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