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Series GSE3384 Query DataSets for GSE3384
Status Public on Jul 21, 2006
Title Nemaline myopathy mouse model
Organism Mus musculus
Experiment type Expression profiling by array
Summary The aim of this study was to investigate the molecular mechanisms implicated in this mouse model of nemaline myopathy, and to further compare the molecular disease response in different skeletal muscles. For this purpose, snap frozen skeletla muscle specimens from wild type and transgenic for alpha tropomyosin slow mice were studied. Five different muscle types were used (diaphragm, plantaris, extensor digitorum longus, tibialis anterior, gastrocnemus). Mice were sacrificed between 7 and 10 months. RNA pools from 3-5 animals were created and each pool was hybridized to a U74Av2 Affymetrix GeneChip. Datasets from 36 GeneChips were included in this study.
Keywords: disease mouse model analysis
 
Overall design 36 skeletal mouse muscle RNA pools were used, from 5 different skeletal muscles, in two different conditions (wild type and transgenic)
 
Contributor(s) Sanoudou D, Beggs AH
Citation(s) 16877500
Submission date Sep 29, 2005
Last update date Feb 18, 2018
Contact name Despina Sanoudou
E-mail(s) dsanoudo@enders.tch.harvard.edu
Phone +30-210-6597453
Fax +30-210-6597545
Organization name Foundation for Biomedical Research, Academy of Athens
Department Molecular Biology
Lab Sanoudou Lab
Street address Soranou Efesiou 4
City Athens
ZIP/Postal code 115 27
Country Greece
 
Platforms (1)
GPL81 [MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Samples (36)
GSM76347 DIA-n7; normal diaphragm 7 month
GSM76348 DIA-n7-2; normal diaphragm 7 month
GSM76349 DIA-n10; normal diaphragm 10 month
Relations
BioProject PRJNA93519

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE3384_RAW.tar 100.2 Mb (http)(custom) TAR (of CEL, EXP)

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