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Status |
Public on Sep 13, 2013 |
Title |
Transcription profiles of cumulus cells from GnRH agonists and GnRH antagonists treated oocytes at different maturity stages |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Affymetrix gene expression profiling in cumulus cells (CC) retrieved from patients undergoing GnRH agonists and GnRH antagonists IVF treatment. Oocytes from three different maturity stages were considered: metaphase I oocytes (MI), nonfertilized metaphase II (MII) oocytes (MII-NF) and MII oocytes developed to blactocyst stage embryo (MII-BL).
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Overall design |
From 4 GnRH agonist treated patients, CC MI, CC MII-NF and CC MII-BL samples were collected; from 5 GnRH agonist and 6 GnRH antagonist treated patients, CC MII-NF and CC MII-BL samples were collected; and from 2 GnRH agonist and 4 GnRH antagonist treated patients, CC MI and CC MII-BL were collected. Altogether, 10 CC MI, 15 CC MII-NF and 21 CC MII-BL were collected and considered for transcriptome analysis.
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Contributor(s) |
Devjak R, Fon Tacer K, Juvan P, Virant Klun I, Rozman D, Vrtačnik Bokal E |
Citation(s) |
23082142 |
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Submission date |
Dec 07, 2011 |
Last update date |
Jul 26, 2018 |
Contact name |
Peter Juvan |
Phone |
+386 1 543 7595
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Organization name |
Faculty of Medicine, University of Ljubljana
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Department |
Institute of Biochemistry
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Lab |
Center for Functional Genomics and Bio-Chips
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Street address |
Zaloska 4
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City |
Ljubljana |
ZIP/Postal code |
SI-1000 |
Country |
Slovenia |
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Platforms (1) |
GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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Samples (46)
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GSM845140 |
MII-NF, GnRH Agonist, patient AH |
GSM845141 |
MI, GnRH Agonist, patient AL |
GSM845142 |
MII-BL, GnRH Agonist, patient AL |
GSM845143 |
MII-NF, GnRH Agonist, patient AM |
GSM845144 |
MII-BL, GnRH Agonist, patient AM |
GSM845145 |
MII-NF, GnRH Antagonist, patient AO |
GSM845146 |
MII-BL, GnRH Antagonist, patient AO |
GSM845147 |
MII-BL, GnRH Agonist, patient AS |
GSM845148 |
MII-NF, GnRH Agonist, patient AS |
GSM845149 |
MII-NF, GnRH Antagonist, patient AT |
GSM845150 |
MII-BL, GnRH Antagonist, patient AT |
GSM845151 |
MII-NF, GnRH Agonist, patient AU |
GSM845152 |
MII-BL, GnRH Agonist, patient AU |
GSM845153 |
MII-NF, GnRH Agonist, patient B |
GSM845154 |
MII-BL, GnRH Agonist, patient B |
GSM845155 |
MII-NF, GnRH Agonist, patient BA |
GSM845156 |
MII-BL, GnRH Agonist, patient BA |
GSM845157 |
MII-BL, GnRH Antagonist, patient BB |
GSM845158 |
MII-NF, GnRH Antagonist, patient BB |
GSM845159 |
MII-BL, GnRH Agonist, patient BC |
GSM845160 |
MII-NF, GnRH Agonist, patient BC |
GSM845161 |
MII-BL, GnRH Antagonist, patient BD |
GSM845162 |
MI, GnRH Antagonist, patient BD |
GSM845163 |
MII-NF, GnRH Agonist, patient BF (1) |
GSM845164 |
MII-BL, GnRH Agonist, patient BF |
GSM845165 |
MII-BL, GnRH Antagonist, patient D |
GSM845166 |
MI, GnRH Antagonist, patient D |
GSM845167 |
MI, GnRH Antagonist, patient G |
GSM845168 |
MII-BL, GnRH Antagonist, patient G |
GSM845169 |
MII-BL, GnRH Antagonist, patient J |
GSM845170 |
MI, GnRH Antagonist, patient J |
GSM845171 |
MII-BL, GnRH Agonist, patient L |
GSM845172 |
MI, GnRH Agonist, patient L |
GSM845173 |
MII-NF, GnRH Antagonist, patient P |
GSM845174 |
MII-BL, GnRH Antagonist, patient P |
GSM845175 |
MII-NF, GnRH Antagonist, patient T |
GSM845176 |
MII-BL, GnRH Antagonist, patient T |
GSM845177 |
MII-BL, GnRH Agonist, patient AT |
GSM845178 |
MI, GnRH Agonist, patient AT |
GSM845179 |
MII-NF, GnRH Agonist, patient AT |
GSM845180 |
MI, GnRH Agonist, patient AS |
GSM845181 |
MI, GnRH Agonist, patient AU |
GSM845182 |
MII-NF, GnRH Agonist, patient BF (2) |
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Relations |
BioProject |
PRJNA149789 |
Supplementary file |
Size |
Download |
File type/resource |
GSE34230_RAW.tar |
183.9 Mb |
(http)(custom) |
TAR (of CEL) |
Processed data included within Sample table |
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