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Status |
Public on Dec 31, 2012 |
Title |
Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in adenoid cystic carcinoma of the head and neck |
Organism |
Homo sapiens |
Experiment type |
Genome variation profiling by genome tiling array
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Summary |
Using high-resolution, array-based comparative genomic hybridization (aCGH), we explored genomic alterations in 40 fresh-frozen ACC samples, the largest cohort to date, with the aims to: (1) identify recurrent CNAs in ACC; (2) identify novel candidate target genes; and (3) correlate recurrent CNAs with tumour grade and other clinical parameters to identify potential clinically useful biomarkers.
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Overall design |
High-resolution aCGH on fresh frozen tissue from 40 ACCs.
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Contributor(s) |
Persson M, Andrén Y, Moskaluk CA, Frierson HF, Kling T, Nelander S, Nordkvist A, Persson F, Stenman G |
Citation(s) |
22505352 |
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Submission date |
Jan 03, 2012 |
Last update date |
Jun 25, 2020 |
Contact name |
Marta Persson |
E-mail(s) |
marta.persson@llcr.med.gu.se
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Organization name |
Sahlgrenska Cancer Center
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Street address |
Box 425
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City |
Gotenburg |
ZIP/Postal code |
405 90 |
Country |
Sweden |
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Platforms (1) |
GPL4091 |
Agilent-014693 Human Genome CGH Microarray 244A (Feature number version) |
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Samples (40)
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Relations |
BioProject |
PRJNA150261 |