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| Status |
Public on Feb 22, 2012 |
| Title |
The Polycomb Repressive Complex 2 Is Required For MLL-AF9 Leukemia |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation(s) |
22396593 |
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| Submission date |
Jan 09, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Amit Sinha |
| E-mail(s) |
amit.sinha@childrens.harvard.edu
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| Phone |
617-582-7579
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| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Pediatric Oncology
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| Lab |
Armstrong Lab
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| Street address |
44 Binney St
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| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02135 |
| Country |
USA |
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| Platforms (2) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (23)
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| GSM859567 |
WT MLL-AF9 BM-cells, biological rep1 |
| GSM859568 |
WT MLL-AF9 BM-cells, biological rep2 |
| GSM859569 |
WT MLL-AF9 BM-cells, biological rep3 |
| GSM859570 |
Ezh2-null MLL-AF9 BM-cells, biological rep1 |
| GSM859571 |
Ezh2-null MLL-AF9 BM-cells, biological rep2 |
| GSM859572 |
Ezh2-null MLL-AF9 BM-cells, biological rep3 |
| GSM859573 |
Ezh2-null MLL-AF9 BM-cells, biological rep4 |
| GSM859574 |
Eed-null MLL-AF9 BM-cells, biological rep1 |
| GSM859575 |
Eed-null MLL-AF9 BM-cells, biological rep2 |
| GSM859576 |
Eed-null MLL-AF9 BM-cells, biological rep3 |
| GSM859583 |
WT 2'MLL-AF9 BM-Cells, biological rep1 |
| GSM859584 |
WT 2'MLL-AF9 BM-Cells, biological rep2 |
| GSM859585 |
WT 2'MLL-AF9 BM-Cells, biological rep3 |
| GSM859586 |
WT 2'MLL-AF9 BM-Cells, biological rep4 |
| GSM859587 |
Ezh2-null 2'MLL-AF9 BM-Cells, biological rep1 |
| GSM859588 |
Ezh2-null 2'MLL-AF9 BM-Cells, biological rep2 |
| GSM859589 |
Ezh2-null 2'MLL-AF9 BM-Cells, biological rep3 |
| GSM859590 |
Ezh2-null 2'MLL-AF9 BM-Cells, biological rep4 |
| GSM859591 |
Ezh2-null 2'MLL-AF9 BM-Cells, biological rep5 |
| GSM859592 |
H3K27me3_1'AML_WT |
| GSM859593 |
H3K27me3_1'AML_Ezh2-null |
| GSM859594 |
H3K27me3_2'AML_WT |
| GSM859595 |
H3K27me3_2'AML_Ezh2-null |
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| This SuperSeries is composed of the following SubSeries: |
| GSE34959 |
Expression profiling of primary wild type (WT), Ezh2-null and Eed-null murine MLL-AF9 AML |
| GSE34961 |
Expression profiling of secondary wild type (WT) and Ezh2-null murine MLL-AF9 AML |
| GSE34962 |
Epigenetic profiling of WT and Ezh2-null MLL-AF9 murine leukemic cells |
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| Relations |
| BioProject |
PRJNA150949 |
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