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| Status |
Public on Jan 28, 2012 |
| Title |
Skeletal myoblasts protect cardiomyocytes against oxidative stress via c-Met and epidermal growth factor receptor (EGFR)-dependent paracrine pathways |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
To study the effect of myoblast-derived paracrine factors on cardiomyocyte gene expression, microarray analysis was performed from isolated rat fetal cardiomyocyte cultures. These cultures were treated for 24 hours with fresh culture medium (control), skeletal myoblast-conditioned medium, or cardiac fibroblast-conditioned medium.
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| Overall design |
In total, 3 samples were analyzed.
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| Contributor(s) |
Siltanen A, Nuutila K, Uenaka H, Mäkelä J, Pätilä T, Vento A, Sawa Y, Harjula A, Kankuri E |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jan 27, 2012 |
| Last update date |
Jul 31, 2017 |
| Contact name |
Antti Siltanen |
| Organization name |
University of Helsinki, Institute of Biomedicine
|
| Street address |
Haartmaninkatu 8
|
| City |
Helsinki |
| ZIP/Postal code |
00014 |
| Country |
Finland |
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| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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| Samples (3) |
| GSM867275 |
Isolated cardiomyocytes treated for 24 h with fresh culture medium |
| GSM867276 |
Isolated cardiomyocytes treated for 24 h with myoblast-conditioned medium |
| GSM867277 |
Isolated cardiomyocytes treated for 24 h with cardiac fibroblast-conditioned medium |
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| Relations |
| BioProject |
PRJNA152697 |
