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| Status |
Public on Feb 08, 2012 |
| Title |
Analysis of microRNAs in bovine early embryonic development |
| Platform organisms |
Lemur catta; Saguinus imperator; Ateles sp.; Lagothrix; Macaca mulatta; Macaca nemestrina; Symphalangus syndactylus; Gorilla gorilla; Pan paniscus; Pan troglodytes; Pongo abelii; Homo sapiens; Canis lupus familiaris; Sus scrofa; Bos taurus; Ovis aries; Cricetulus griseus; Mus musculus; Rattus norvegicus; Monodelphis domestica; Rhinopithecus bieti |
| Sample organism |
Bos taurus |
| Experiment type |
Expression profiling by array
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| Summary |
In animals, the maternal-to-embryonic transition (MET) is an important step occurring in the first days of early development. This important transition involves the degradation of maternal transcripts that have been stocked during oogenesis and used until this transition. Moreover, some precise and specific control mechanisms must govern the adequate synchronization of the MET events to promote embryonic genome activation. These mechanisms are not well understood, but microRNAs could be one of the mechanisms involved. MicroRNAs are short non-coding RNAs involved in a growing number of pathways by their post-transcriptional repression of mRNA translation. Thus, we analyzed microRNA expression during oocyte maturation by comparing GV-oocytes with MII-oocytes in cow.
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| Overall design |
Groups of 300 Oocytes_GV and Oocytes_MII were used for miRNA expression analysis. The miRNA expressions were determined using the MiRMammalia_11.0 array from LC Sciences.
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| Contributor(s) |
Mondou E, Dufort I, Sirard M |
| Citation(s) |
22491901 |
| Submission date |
Feb 06, 2012 |
| Last update date |
May 03, 2012 |
| Contact name |
Marc-André Sirard |
| E-mail(s) |
Marc-Andre.Sirard@fsaa.ulaval.ca
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| Organization name |
Université Laval
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| Department |
Sciences Animales
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| Street address |
Offfice 2732, 2440 Hochelaga Blvd.
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| City |
Québec City |
| State/province |
Quebec |
| ZIP/Postal code |
G1V 0A6 |
| Country |
Canada |
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| Platforms (1) |
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| Samples (1) |
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| Relations |
| BioProject |
PRJNA152215 |
