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Series GSE36277 Query DataSets for GSE36277
Status Public on Feb 28, 2015
Title SNP-based LOH of hepatocellular carcinoma (HCC)
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
Summary High frequency of loss of heterozygosity (LOH) at locus D4S2964 was found in hepatocellular carcinoma (HCC) by our previous studies and others’. The present study was designed to explore genes around the locus affected by LOH and their clinical implications. 440 SNPs located at 49 genes around D4S2964 were selected from NCBI website for the SNPs microarray fabrication. LOH of these SNPs markers in 112 cases of HCC tissues and paired adjacent liver tissues were investigated by the SNP microarray. A map of LOH of SNPs in genes around D4S2964 was constructed.
 
Overall design 112 pairs of HCC tissues and corresponding non-tumor tissues was genotyped. LOH and its clinical implication was analyzed.
 
Contributor(s) Huang G, Wang H
Citation(s) 22952874
Submission date Mar 05, 2012
Last update date Sep 19, 2019
Contact name Guo-liang Huang
E-mail(s) huang.glen@gmail.com
Organization name Sun Yat-Sen University
Department Cancer Center
Lab National Key Laboratory of Oncology in South China
Street address 651 Dongfeng East Road
City Guangzhou
ZIP/Postal code 510060
Country China
 
Platforms (1)
GPL15305 SYSUCC human 440 SNPs around D4S2964
Samples (224)
GSM885804 HCC1000N, non-tumor tissue
GSM885805 HCC1000T, tumor tissue
GSM885806 HCC1003N, non-tumor tissue
Relations
BioProject PRJNA153005

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36277_RAW.tar 18.8 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

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