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Series GSE36567 Query DataSets for GSE36567
Status Public on Mar 17, 2012
Title Mll1 regulates the downstream gene transcription activated by TNFa
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Genes of mixed lineage leukemia family regulate transcription via methylating histone H3K4. we studied the role of MLL1 in innate immunity and found it selectively regulates the activation of NF-kB downstream genes mediated by TNFa.
 
Overall design Mll1+/+ and Mll1-/- MEF cells were treated for 4 hr with 10ng/ml TNFa or control solution respectively. The same treatment were performed three times independently and the harvested cells of same treatment were mixed together and submitted for high throughput sequencing.
 
Contributor(s) Wang X, Zhu K, Liao Y, Guo A, Li L, Wu M
Citation(s) 22623725
Submission date Mar 16, 2012
Last update date May 15, 2019
Contact name Min Wu
E-mail(s) wumin@whu.edu.cn
Organization name Wuhan University
Department College of Life Science
Street address Room 5005, College of Life Sciences, Wuhan University
City Wuhan
State/province Hubei
ZIP/Postal code 430072
Country China
 
Platforms (1)
GPL9250 Illumina Genome Analyzer II (Mus musculus)
Samples (4)
GSM896964 Mll1+/+
GSM896965 Mll1+/+ TNF
GSM896966 Mll1 -/-
Relations
SRA SRP011556
BioProject PRJNA153723

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE36567_4samples_RPKM.txt.gz 782.5 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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