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Series GSE39184 Query DataSets for GSE39184
Status Public on Jul 10, 2012
Title Contact versus contactless signatures in leukemia
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene expression profile (GEP) was analyzed in bone marrow (BM) samples from patients with leukemia or leukemic phase of lymphoma at different time points following aspiration. Among numerous changes in GEP evolved over time a discrete subset of > 60 genes exhibited prompt and sustained switch in expression consistently. Similar results were discovered recently in BM samples from patients with multiple myeloma (GSE36036). GEP was also examined in peripheral blood as well as in BM samples depleted of red blood cells (=WBC) and in cultured cells from some of the patients.
 
Overall design Comparative gene expression profiling of whole bone marrow samples from patients with leukemia fixed either immediately following aspiration or after delayed RNA fixation. Comparison was also made between cultured bone marrow cells fixed immediately following spread from the bottom well versus after maintenance in suspension (for 120 minutes).
 
Contributor(s) Cohen Y, Garach-Jehoshua O, Bar-Chaim A, Kornberg A
Citation(s) 23241658
Submission date Jul 09, 2012
Last update date Jul 26, 2018
Contact name Yossi Cohen
E-mail(s) yosefc@asaf.health.gov.il
Phone 972-8-9778222
Fax 972-8-9779772
Organization name Asaf Harofeh University Hospital
Department Hematology
Street address Zeriffin
City Be'er Yacob
ZIP/Postal code 97300
Country Israel
 
Platforms (1)
GPL6244 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Samples (17)
GSM957662 CaseA (DLBCL) 0 min [BM]
GSM957663 CaseA (DLBCL) 83 min [BM]
GSM957664 CaseB (APL) 0 min [BM]
Relations
BioProject PRJNA170174

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE39184_RAW.tar 65.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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