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Status |
Public on Oct 01, 2012 |
Title |
Comparison of Zmiz1-induced keratoancanthoma and normal skin |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Transgenic mice expressing a truncated form of Zmiz1 in the skin develop spontaneous keratoacanthomas. In this experiment, a Cre-inducible transgene expressing a truncated form of Zmiz1 was introduced into mice. Activation of the transgene in these mice was achieved by breeding to K14-Cre transgenic animals. Double transgenic mice formed spontaenous keratoacanthomas with short latency.
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Overall design |
In this experiment, we generated gene expression profiles for five Zmiz1-induced keratoacanthomas and six normal skin samples.
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Contributor(s) |
Dupuy AJ |
Citation missing |
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Submission date |
Jul 13, 2012 |
Last update date |
Oct 02, 2012 |
Contact name |
Adam Dupuy |
E-mail(s) |
adam-dupuy@uiowa.edu
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Phone |
319-335-8090
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Fax |
319-335-7198
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Organization name |
University of Iowa
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Street address |
51 Newton Road
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City |
Iowa City |
ZIP/Postal code |
52242 |
Country |
USA |
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Platforms (1) |
GPL10740 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [probe set (exon) version] |
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Samples (11)
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Relations |
BioProject |
PRJNA170737 |