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| Status |
Public on Jan 10, 2006 |
| Title |
Pac1+/+ versus Pac1-/- TG-macrophages_LPS 6h |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
LPS-stimulated macrophages from Pac1+/+ and Pac1-/- mice were compared to assess gene expression changes in the absence of PAC-1 (also known as Dual specificity phosphatase 2).
Keywords: Comparison of Pac1+/+ with Pac1-/- activated macrophages
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| Overall design |
Age matched Pac1+/+ and Pac1-/- littermates were used to obtain equal numbers of thiolycollate-elicited macrophages. Pure populations of macrophages were stimulated with 100 ng/ml of LPS for 6 hours. 6 hours was chosen to assess mainly inflammatory gene expression.
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| Contributor(s) |
Jeffrey KL, Mackay CR |
| Citation missing |
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| |
| Submission date |
Jan 06, 2006 |
| Last update date |
Jul 06, 2016 |
| Contact name |
Charles Reay Mackay |
| E-mail(s) |
c.mackay@garvan.org.au
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| Phone |
+61-2-92958405
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| Fax |
+61-2-92958404
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| Organization name |
Garvan Institute for Medical Research
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| Street address |
384 Victoria St
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| City |
Darlinghurst |
| State/province |
NSW |
| ZIP/Postal code |
2010 |
| Country |
Australia |
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| Platforms (1) |
| GPL32 |
[MG_U74A] Affymetrix Murine Genome U74A Array |
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| Samples (2) |
| GSM91224 |
Pac-1-/- TG-macrophages_LPS 6h |
| GSM91225 |
Wild-type TG-macrophages_LPS 6h |
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| This SubSeries is part of SuperSeries: |
| GSE4014 |
Pac1+/+ versus Pac1-/- in macrophages and mast cells |
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| Relations |
| BioProject |
PRJNA104885 |
