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Status |
Public on Jan 10, 2006 |
Title |
Pac1+/+ versus Pac1-/- TG-macrophages_LPS 6h |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
LPS-stimulated macrophages from Pac1+/+ and Pac1-/- mice were compared to assess gene expression changes in the absence of PAC-1 (also known as Dual specificity phosphatase 2). Keywords: Comparison of Pac1+/+ with Pac1-/- activated macrophages
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Overall design |
Age matched Pac1+/+ and Pac1-/- littermates were used to obtain equal numbers of thiolycollate-elicited macrophages. Pure populations of macrophages were stimulated with 100 ng/ml of LPS for 6 hours. 6 hours was chosen to assess mainly inflammatory gene expression.
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Contributor(s) |
Jeffrey KL, Mackay CR |
Citation missing |
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Submission date |
Jan 06, 2006 |
Last update date |
Jul 06, 2016 |
Contact name |
Charles Reay Mackay |
E-mail(s) |
c.mackay@garvan.org.au
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Phone |
+61-2-92958405
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Fax |
+61-2-92958404
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Organization name |
Garvan Institute for Medical Research
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Street address |
384 Victoria St
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City |
Darlinghurst |
State/province |
NSW |
ZIP/Postal code |
2010 |
Country |
Australia |
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Platforms (1) |
GPL32 |
[MG_U74A] Affymetrix Murine Genome U74A Array |
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Samples (2) |
GSM91224 |
Pac-1-/- TG-macrophages_LPS 6h |
GSM91225 |
Wild-type TG-macrophages_LPS 6h |
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This SubSeries is part of SuperSeries: |
GSE4014 |
Pac1+/+ versus Pac1-/- in macrophages and mast cells |
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Relations |
BioProject |
PRJNA104885 |