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Series GSE4091 Query DataSets for GSE4091
Status Public on Dec 01, 2007
Title Histone turnover mediates epigenetic processes in Drosophila S2 cells
Organism Drosophila melanogaster
Experiment type Genome binding/occupancy profiling by genome tiling array
Summary Histone H3 is assembled into nucleosomes during replication but is replaced by the H3.3 variant at sites of active transcription. Thus replacement levels provide a quantitative measure of histone turnover during transcriptional elongation and other active processes in dividing cells. Here we provide new insights into epigenetic regulation with the first genome-wide chromatin profile at 100-bp resolution, based on measurements of H3.3 levels throughout the Drosophila genome. These data are unpublished.
Keywords: Chromatin affinity-purification on microarray
Overall design Chromatin affinity profiling of histones H3 and H3.3 on Drosophila tiling arrays
Web link
Contributor(s) Mito Y, Henikoff JG, Henikoff S
Citation(s) 17347439
Submission date Jan 24, 2006
Last update date Apr 18, 2012
Contact name Jorja Henikoff
Phone 206-667-4850
Organization name Fred Hutchinson Cancer Research Center
Department Basic Sciences
Lab Henikoff
Street address 1100 Fairview AV N, A1-162
City Seattle
State/province WA
ZIP/Postal code 98109-1024
Country USA
Platforms (3)
GPL3352 FHCRC DMEL 4.2 Tiling 1 of 3
GPL3353 FHCRC DMEL 4.2 Tiling 2 of 3
GPL3354 FHCRC DMEL 4.2 Tiling 3 of 3
Samples (6)
GSM93208 58906 H3_1/Input_1
GSM93209 58885 H33FL_1/INPUT_2
GSM93210 58588 H3_1/Input_1
BioProject PRJNA95249

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE4091_RAW.tar 6.4 Mb (http)(custom) TAR (of BEDGRAPH, GFF)

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