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Series GSE41635 Query DataSets for GSE41635
Status Public on Oct 17, 2012
Title Expression data from ALK over-expressed MCF-7 clones and control clones
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To evaluate the function of ALK in breast cancer, we enforcing expressed full length wild type ALK in the parental MCF-7 breast cancer cell line that we have established in previous studies have a very low invasive capacity, do not form tumor emboli nor do they invade into the dermal lymphatics when grown as xenografts.
Overall design Whole unbiased transcriptome analysis were performed using ALK over-expressed MCF-7 clones and control clones. Pathway mapping revealed that the presence of ALK induced up and down regulation changes of series of genes within several canonical signal pathway.
Contributor(s) Luo A
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Submission date Oct 16, 2012
Last update date Mar 25, 2019
Contact name Annie Z Luo
Phone 713-745-5516
Fax 713-745-9231
Organization name M D Anderson Cancer Center
Department Experimental Therapeutics
Lab Dr. Robertson
Street address 1901 East Road 4SCR3.1004
City Houston
State/province Texas
ZIP/Postal code 77230-1429
Country USA
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (4)
GSM1020604 MCF-7 breast cancer cell line, Control clones, 3D
GSM1020605 MCF-7 breast cancer cell line, Control clones, 3D, 2nd sample
GSM1020606 MCF-7 breast cancer cell line, ALK over-expressed clones, 3D
BioProject PRJNA177775

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE41635_15721_alk_vs_ctr_group_1.5_fold_8-22-12.xlsx.gz 1004.1 Kb (ftp)(http) XLSX
GSE41635_RAW.tar 32.1 Mb (http)(custom) TAR (of CEL, DCP)
Processed data included within Sample table
Processed data are available on Series record

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