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| Status |
Public on Oct 17, 2012 |
| Title |
Expression data from ALK over-expressed MCF-7 clones and control clones |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To evaluate the function of ALK in breast cancer, we enforcing expressed full length wild type ALK in the parental MCF-7 breast cancer cell line that we have established in previous studies have a very low invasive capacity, do not form tumor emboli nor do they invade into the dermal lymphatics when grown as xenografts.
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| Overall design |
Whole unbiased transcriptome analysis were performed using ALK over-expressed MCF-7 clones and control clones. Pathway mapping revealed that the presence of ALK induced up and down regulation changes of series of genes within several canonical signal pathway.
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| Contributor(s) |
Luo A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Oct 16, 2012 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Annie Z Luo |
| E-mail(s) |
azluo@mdanderson.org
|
| Phone |
713-745-5516
|
| Fax |
713-745-9231
|
| Organization name |
M D Anderson Cancer Center
|
| Department |
Experimental Therapeutics
|
| Lab |
Dr. Robertson
|
| Street address |
1901 East Road 4SCR3.1004
|
| City |
Houston |
| State/province |
Texas |
| ZIP/Postal code |
77230-1429 |
| Country |
USA |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (4)
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| GSM1020604 |
MCF-7 breast cancer cell line, Control clones, 3D |
| GSM1020605 |
MCF-7 breast cancer cell line, Control clones, 3D, 2nd sample |
| GSM1020606 |
MCF-7 breast cancer cell line, ALK over-expressed clones, 3D |
| GSM1020607 |
MCF-7 breast cancer cell line, ALK over-expressed clones, 3D, 2nd sample |
|
| Relations |
| BioProject |
PRJNA177775 |
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