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Series GSE4313 Query DataSets for GSE4313
Status Public on Jun 15, 2006
Title Effect of posttranslational modifications of SATB1 on its ability to regulate global gene expression in HeLa Cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene profiling studies using RNA from HeLa cells overexpressing point mutants of SATB1 defective in phosphorylation or acetylation unequivocally demonstrated the importance of these modifications towards the ability of SATB1 to act as a global regulator of gene expression. HeLa cells were chosen as a representative of non-T cells, and do not express SATB1 endogenously.
Keywords: cDNA array
 
Overall design Total RNA from untransfected HeLa cells was used as reference and was labeled with Cy5. Total RNA from HeLa cells stably transfected with wild type, or S185A, or K136A mutant SATB1 expressing construct was used as experimental sample and was labeled with Cy3.
 
Contributor(s) Kumar P, Notani D, Kumar C, Galande S
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Submission date Mar 01, 2006
Last update date Mar 17, 2012
Contact name Sanjeev Galande
E-mail(s) sanjeev@nccs.res.in
Phone 91-20-25690922
Fax 91-20-25692259
Organization name National Centre for Cell Science
Lab Chromatin Biology Laboratory
Street address Ganeshkhind
City Pune
ZIP/Postal code 411007
Country India
 
Platforms (1)
GPL3494 UHN Human 19K EST array
Samples (3)
GSM98547 Global regulation of gene expression by SATB1 in HeLa cells from Galande Lab
GSM98585 Effect of S185A mutation on global gene regulation by SATB1 in HeLa cells from Galande Lab
GSM98586 Effect of K136A mutation on global gene regulation by SATB1 in HeLa cells from Galande Lab
This SubSeries is part of SuperSeries:
GSE4317 Effect of post-translational modifications of SATB1 on global gene expression in HeLa and Jurkat T cells
Relations
BioProject PRJNA104649

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE4313_RAW.tar 7.1 Mb (http)(custom) TAR (of GPR)

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