|
Status |
Public on Feb 14, 2013 |
Title |
Bisulfite-Seq profiling of undifferentiated ESCs, and in vitro derived primordial germ cells (iPGCs) |
Organism |
Mus musculus |
Experiment type |
Methylation profiling by high throughput sequencing
|
Summary |
We report that in vitro derived PGCs undergo genome-wide DNA demethylation and that this demethylation does not require Tet1/Tet2
|
|
|
Overall design |
Examination of methylation in ESCs, iPGCs, and Tet2-/- iPGCs depleted of Tet1 by shRNA lentiviruses
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Contributor(s) |
Vincent JJ, Clark AT |
Citation(s) |
23415914 |
Submission date |
Feb 05, 2013 |
Last update date |
May 15, 2019 |
Contact name |
John Vincent |
E-mail(s) |
jvincent@ucla.edu
|
Organization name |
UCLA
|
Department |
MCDB
|
Street address |
621 Charles E Young Dr. S
|
City |
Los Angeles |
ZIP/Postal code |
90095 |
Country |
USA |
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|
Platforms (2) |
GPL9250 |
Illumina Genome Analyzer II (Mus musculus) |
GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
Samples (12)
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Relations |
BioProject |
PRJNA189191 |
SRA |
SRP018523 |