|
| Status |
Public on Jun 21, 2013 |
| Title |
Gene expression in Early-Onset Preeclampsia Placentas and Controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We investigated the DNA methylation and gene expression of 20 chorionic villi samples from early onset preeclampsia placentas to 20 gestational age matched controls. From this we were able to see a widespread disregulation in DNA methylation across a subset of genes in the genome. This may help to elucidate the underlying biological problems that lead to early onset preeclampsia. We noted that there were DNA methylation changes in many genes of importance as well as in different genomic elements such as enhancers.
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| |
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| Overall design |
RNA from 8 Early Onset Preeclampsia placentas and 8 gestational age matched controls
|
| |
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| Contributor(s) |
Blair JD, Yuen RK, von Dadelszen P, Robinson WP |
| Citation(s) |
23770704 |
| |
| Submission date |
Feb 27, 2013 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Wendy Robinson |
| E-mail(s) |
wprobinsonlab@gmail.com
|
| Organization name |
University of British Columbia
|
| Department |
Medical Genetics
|
| Lab |
Robinosn
|
| Street address |
950 W 28th Ave
|
| City |
Vancouver |
| State/province |
BC |
| ZIP/Postal code |
V5Z 4H4 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (16)
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| This SubSeries is part of SuperSeries: |
| GSE44712 |
Early-Onset Preeclampsia Placentas and Controls |
|
| Relations |
| BioProject |
PRJNA191070 |
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