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| Status |
Public on Oct 17, 2013 |
| Title |
Global gene expression analysis of vascular progenitors differentiated from human embryonic stem cells or induced pluripotent stem cells, corresponding donor starting cells, and mature human endothelial cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Global gene expression analysis of FACS-purified CD31+CD146+ vascular progenitors (VP) derived from (a) human embryonic stem cells (VP-hESC), (b) adult fibroblast derived induced pluripotent stem cells (VP-AdF-iPSC), (c) stromal primed cord blood CD34+ myeloid progenitor derived iPSC (VP-sp-CB-iPSC), (d) corresponding starting fibroblasts and myeloid progenitors, (e) human umbilical vein endothelial cells, and (f) human dermal microvascular endothelial cells.
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| Overall design |
Total RNA was harvested from (a) adult fibroblasts, (b) human myeloid progenitors: Non-nucloefected CD34+ CB cells that were expanded with growth factors from Day -3 until Day 0 and harvested, (c) FACS-purified CD31+CD146+ vascular progenitors (VP) that were differentiated from human embryonic stem cells (hESC), (d) VP differentiated from low passage stromal-primed episomal iPSC derived from growth-factor activated cord blood myeloid progenitors, (e) VP differentiated from iPSC derived from adult fibroblasts, (f) human umbilical vein endothelial cells, and (g) human dermal microvascular endothelial cells.. Illumina HumanHT-12 V4.0 expression beadchips were used for all analyses in this series. Three or independent samples of each sample type were each run on individual microarrays.
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| Contributor(s) |
Park TS, Zimmerlin L, Huo JS, Talbot CC, Aguilar J, Yu W, Zambidis ET |
| Citation(s) |
24163065 |
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| Submission date |
Mar 06, 2013 |
| Last update date |
Jan 28, 2016 |
| Contact name |
Elias Thomas Zambidis |
| Organization name |
Johns Hopkins School of Medicine
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| Department |
Oncology
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| Street address |
733 N. Broadway
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| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21205 |
| Country |
USA |
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| Platforms (1) |
| GPL10904 |
Illumina HumanHT-12 V4.0 expression beadchip (gene symbol) |
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| Samples (27)
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| GSM1093989 |
Human umbilical vein endothelial cells, sample 3 |
| GSM1093990 |
Human umbilical vein endothelial cells, sample 2 |
| GSM1093991 |
Human umbilical vein endothelial cells, sample 1 |
| GSM1093992 |
Human dermal microvascular endothelial cells, sample 3 |
| GSM1093993 |
Human dermal microvascular endothelial cells, sample 2 |
| GSM1093994 |
Human dermal microvascular endothelial cells, sample 1 |
| GSM1093995 |
FACS-purified CD31+/CD146+ vascular progenitors derived from hESC (H9) p51 |
| GSM1093996 |
FACS-purified CD31+/CD146+ vascular progenitors derived from hESC (ES03) p80 |
| GSM1093997 |
FACS-purified CD31+/CD146+ vascular progenitors derived from hESC (H9) p52 |
| GSM1093998 |
FACS-purified CD31+/CD146+ vascular progenitors derived from hESC (H9) p56 |
| GSM1093999 |
FACS-purified CD31+/CD146+ vascular progenitors derived from nonviral 7F stromal primed cord blood iPSC clone 6.13 p21 |
| GSM1094000 |
FACS-purified CD31+/CD146+ vascular progenitors derived from nonviral 7F stromal primed cord blood iPSC clone 19.11 p19 |
| GSM1094001 |
FACS-purified CD31+/CD146+ vascular progenitors derived from nonviral 4F stromal primed cord blood iPSC clone E17C6 p17 |
| GSM1094002 |
FACS-purified CD31+/CD146+ vascular progenitors derived from nonviral 7F stromal primed cord blood iPSC clone 6.2 p31 |
| GSM1094003 |
FACS-purified CD31+/CD146+ vascular progenitors derived from viral 4F Adult Fibroblast iPSC clone HUF3 p30 |
| GSM1094004 |
FACS-purified CD31+/CD146+ vascular progenitors derived from viral 4F Adult Fibroblast iPSC clone HUF1 p12 |
| GSM1094005 |
FACS-purified CD31+/CD146+ vascular progenitors derived from viral 4F Adult Fibroblast iPSC clone HUF5 p29 |
| GSM1094006 |
FACS-purified CD31+/CD146+ vascular progenitors derived from viral fibroblast iPSC line IMR90-1 p61 |
| GSM1094007 |
Fibroblast Day zero, Sample 3 |
| GSM1094008 |
Fibroblast Day zero, Sample 1 |
| GSM1094009 |
Fibroblast Day zero, Sample 2 |
| GSM1094010 |
hESC (H9) p52 |
| GSM1094011 |
hESC (H9) p51 |
| GSM1094012 |
hESC (H9) p18 |
| GSM1094013 |
Cord Blood Day zero, Sample 3 |
| GSM1094014 |
Cord Blood Day zero, Sample 2 |
| GSM1094015 |
Cord Blood Day zero, Sample 1 |
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| Relations |
| BioProject |
PRJNA192534 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE44926_non_normalized.txt.gz |
14.3 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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