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| Status |
Public on Feb 24, 2016 |
| Title |
Studies on progenitor endothelial cells; exploring mechanisms for improvement of cardiovascular diseases |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptomic analysis of primary CD34+ cells. CD34+ cell were induced in vitro with hypoxia (3 hours), high glucose and high glucose plus hypoxia. Subsequently, the effect of metformin (anti-diabetic drug) on all conditions was studied to take advantage of transcriptomics to prospectively explore the mechanism of this drug to reduce the risk of cardiovascular diseases in type II diabetic patients.
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| |
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| Overall design |
Total RNA isolated from 20 samples; 10 different conditions each has 2 repeats; labeled, and hybridized to Affymetrix Human Gene 1.0 ST Array.
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| |
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| Contributor(s) |
Bakhashab S, Weaver J, Spyridopoulos I, Schulten H, Manikandan J, Lary S, Ahmed F, Alqahtani MH |
| Citation(s) |
26861446 |
| |
| Submission date |
Apr 22, 2013 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Sherin Bakhashab |
| E-mail(s) |
sbakhashab@kau.edu.sa
|
| Organization name |
King Abdulaziz University
|
| Department |
Biochemistry
|
| Street address |
Abdullah Sulyman
|
| City |
Jeddah |
| ZIP/Postal code |
21589 |
| Country |
Saudi Arabia |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA198490 |
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