|
| Status |
Public on Jan 06, 2014 |
| Title |
Genome-wide DNA methylation in cervical tissue |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
|
| Summary |
The aim of this study was to identify new candidate genes that are differentially methylated in squamous cell carcinoma compared to the DNA samples from cervical intraepithelial neoplasia grade 3 (CIN3) and normal cervical scrapes. The Illumina Infinium Human Methylation 450 K BeadChip method identifies genome-wide DNA methylation changes in CpG islands, CpG shores and shelves.
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| |
|
| Overall design |
In this study 20 normal cervical samples (HPV negative), 18 samples with CIN3 lesions (HPV positive) and 6 cervical cancer tissues (HPV positive) were included.
|
| |
|
| Contributor(s) |
Farkas SA, Milutin-Gašperov N, Grce M, Nilsson TK |
| Citation(s) |
24030264 |
| |
| Submission date |
Apr 23, 2013 |
| Last update date |
Mar 22, 2019 |
| Contact name |
Sanja A Farkas |
| E-mail(s) |
sanja.farkas@orebroll.se
|
| Organization name |
Örebro University hospital
|
| Department |
Laboratory medicine
|
| Street address |
Södra rosen grevsgatan
|
| City |
Örebro |
| ZIP/Postal code |
701 85 |
| Country |
Sweden |
| |
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| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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| Samples (44)
|
|
| Relations |
| BioProject |
PRJNA198713 |
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