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| Status |
Public on Jul 23, 2013 |
| Title |
ETV4 promotes metastasis in response to combined activation of PI3kinase and RAS signaling in a mouse model of advanced prostate cancer |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of the transcriptome of mouse models of prostate cancer. NP (Nkx3.1CreERT2/+; Ptenfloxed/floxed) mice develop non-metastatic tumors while NPK (Nkx3.1CreERT2/+; Ptenfloxed/floxed; KrasG12D/+) mice develop metastatic tumors
The NPK mice are also analyzed at early and late stages of tumorigenesis (1 vs. 3 months after induction)
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| |
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| Overall design |
Total RNA obtained from prostate tumors of different genotypes and at different stages of dissease as indicated
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| |
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| Contributor(s) |
Aytes A, Mitrofanova A, Kinkade CW, Lefebvre C, Lei M, Phelan V, Le HC, Koutcher JA, Cardiff RD, Califano A, Shen MM, Abate-Shen C |
| Citation(s) |
23918374 |
| |
| Submission date |
Jun 06, 2013 |
| Last update date |
Jan 16, 2019 |
| Contact name |
Antonina Mitrofanova |
| E-mail(s) |
mitrofanova.antonina@hotmail.com
|
| Organization name |
Rutgers University
|
| Street address |
65 Bergen Street, Rm 923B
|
| City |
Newark |
| State/province |
NJ |
| ZIP/Postal code |
07107 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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| Samples (21)
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| Relations |
| BioProject |
PRJNA207330 |
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