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| Status |
Public on Nov 01, 2018 |
| Title |
Transcriptional difference between wild-type and zip-3(gk3164) |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by array
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| Summary |
ATFS-1 has been shown to regulate transcription of mitochondrial chaperone genes such as mtHsp70/hsp-6 and hsp-60 in response to mitocondrial stress. To identify the entire ATFS-1-mediated response, we compared the transcript profiles from wild-type and atfs-1(tm4525) worms raised in the absence and presence of mitochondrial stress.
We used microarrays to identify genes regulated by ZIP-3
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| Overall design |
RNA samples were prepared from wild-type(wt) and zip-3(gk3164)(mutant) worms fed either control(RNAi). Worms were synchronized by bleaching, raised in liquid culture and harvested at the L4 stage. Each experiment was performed in triplicate indicated as 1,2 and 3.
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| Contributor(s) |
Nargund A, Haynes C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 02, 2013 |
| Last update date |
Nov 01, 2018 |
| Contact name |
Jeffrey Zhao |
| Organization name |
Memorial Sloan Kettering Cancer Center
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| Department |
Genomics Core
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| Street address |
1275 York Avenue
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
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| Platforms (1) |
| GPL200 |
[Celegans] Affymetrix C. elegans Genome Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA210331 |
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