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Status |
Public on Jul 31, 2007 |
Title |
Methylation profiling in pediatric medulloblastoma |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by genome tiling array
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Summary |
Whole-genome screening of CpG Island methylation status by array-based profiling of absolute methylation status (array-PAMS). Keywords: methylation profiling, pediatric medulloblastoma, single sample
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Overall design |
Methylation-specifically digested DNA (Cy3) was hybridized against methylation-sensitively digested DNA (Cy5) from the same sample. CGI methylation in 20 pediatric medulloblastomas (M) and normal cerebellum (Cb, pool of five unaffected donors, age 25–33 years)
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Contributor(s) |
Pfister SM, Schlaeger C, Radlwimmer B, Lichter P |
Citation(s) |
- Pfister S, Schlaeger C, Mendrzyk F, Wittmann A et al. Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma. Nucleic Acids Res 2007;35(7):e51. PMID: 17344319
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Submission date |
May 17, 2006 |
Last update date |
Mar 16, 2012 |
Contact name |
Stefan M Pfister |
E-mail(s) |
s.pfister@dkfz.de
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Phone |
+49 6221 424593
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Fax |
+49 6221 424639
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URL |
http://www.dkfz.de/en/genetics/staff/staff_detail/s_pfister.html
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Organization name |
German Cancer Research Center
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Department |
Molecular Genetics
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Lab |
P. Lichter
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Street address |
INF 580
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City |
Heidelberg |
ZIP/Postal code |
69120 |
Country |
Germany |
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Platforms (1) |
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Samples (22)
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Relations |
BioProject |
PRJNA95829 |