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Status |
Public on Jul 16, 2013 |
Title |
Cyclin D1 determines estrogen depependent signaling in mouse mammary gland. |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Ovariectomized virgin Ccnd1-/- and Ccnd1+/+ mice (5 weeks of age) were allowed to recuperate for 2 weeks. The mice were assigned to either replacement pellets containing E2 (0.75 mg, 60-day release) or pellet containing placebo. Mice were sacrificed at day 7 after pellet implantation. RNA extracted from mammary glands (3 each group) was labeled and used to probe Affymetrix 430_2.0 arrays.
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Overall design |
Six separate control Ccnd1+/+ C57BL/6 were compared to six Ccnd1-/- C57BL/6 mice. 3 mice in each group treated with placebo and three mice treated with E2
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Contributor(s) |
Casimiro MC, Pestell RG |
Citation(s) |
23864650 |
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Submission date |
Jul 15, 2013 |
Last update date |
Feb 11, 2019 |
Contact name |
Mathew Casimiro Casimiro |
Organization name |
Thomas Jefferson University
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Department |
233 South 10th St, Rm 1035
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Lab |
Philadelphia
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Street address |
233 South 10th St, Rm 1035
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City |
19107 |
State/province |
United States |
ZIP/Postal code |
Mathew Casimiro |
Country |
USA |
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Platforms (1) |
GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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Samples (12)
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GSM1186322 |
Mouse mammary gland Ccnd1+/+ Vehicle Rep1 |
GSM1186323 |
Mouse mammary gland Ccnd1+/+ Vehicle Rep2 |
GSM1186324 |
Mouse mammary gland Ccnd1+/+ Vehicle Rep3 |
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Relations |
BioProject |
PRJNA212122 |