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Status |
Public on Jan 01, 2015 |
Title |
Mucosal gene expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC) |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.
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Overall design |
Colonic mucosal biopsies were obtained during endoscopy from 13 UC (7 active and 6 inactive) patients and 8 normal controls. Total RNA was isolated from colonic mucosal biopsies, labelled and hybridized to Affymetrix Genechip Human Gene 1.0ST Arrays.
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Contributor(s) |
Van der Goten J, Van Lommel L, Ferrante M, Van Assche G, Rutgeerts P, Schuit F, Vermeire S, Arijs I |
Citation(s) |
25546151 |
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Submission date |
Jul 17, 2013 |
Last update date |
Jul 26, 2018 |
Contact name |
Jan Van der Goten |
E-mail(s) |
jan.vandergoten@med.kuleuven.be
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Organization name |
KU Leuven
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Department |
Clinical and Experimental Medicine
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Lab |
TARGID - IBD Leuven
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Street address |
Herestraat 49 bus 701
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City |
Leuven |
ZIP/Postal code |
3000 |
Country |
Belgium |
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Platforms (1) |
GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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Samples (21)
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This SubSeries is part of SuperSeries: |
GSE48959 |
Mucosal expression profiling in (un)inflamed colon of patients with ulcerative colitis (UC) |
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Relations |
BioProject |
PRJNA212400 |