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| Status |
Public on Jun 30, 2014 |
| Title |
microRNA expression profiling in TPC1 cell line treated with the RTK inhibitor RPI-1 |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
We treated the papillary thyroid carcinoma-derived cell line TPC1 with the RTK inhibitor RPI-1 to obtain a thyroid carcinoma cell model. The RET tyrosine kinase is a target of the inhibitor. microRNA expression changes were evaluated comparing cells treated with the inhibitor fo 24 hours versus cells treated with DMSO for 24 hours.
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| Overall design |
Biological triplicates for RPI-1 and DMSO treated cells were generated by independent treatments and total RNA extractions. One sample from each class did not pass quality control, and thus was discarded. The final dataset comprises two samples for each class.
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| Contributor(s) |
Borrello MG, Minna E, Romeo P, Cassinelli G, Lanzi C, Degl'Innocenti D, De Cecco L, Dugo M |
| Citation(s) |
24810336 |
| |
| Submission date |
Jul 31, 2013 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Matteo Dugo |
| E-mail(s) |
dugo.matteo@hsr.it
|
| Organization name |
IRCCS Ospedale San Raffaele
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| Department |
Department of Medical Oncology
|
| Street address |
via Olgettina 60
|
| City |
Milan |
| ZIP/Postal code |
20132 |
| Country |
Italy |
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| Platforms (1) |
| GPL8179 |
Illumina Human v2 MicroRNA expression beadchip |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE49415 |
hsa-miR-199a-3p is an oncosuppressor microRNA in papillary thyroid carcinoma |
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| Relations |
| BioProject |
PRJNA213905 |
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