|
| Status |
Public on Jan 06, 2014 |
| Title |
Gene expression in intestinal epithelial crypt and villus cell populations |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We analyzed gene expression profiles in isolated mouse LGR5+ intestinal stem cells, lineage-specific enterocyte and secretory progenitors, and terminally differentiated villus enterocytes. Gene Ontology analyses of cell type-specific transcripts indicated their expected biological functions.
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| |
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| Overall design |
We hybridized Affmetrix 430A 2.0 mouse microarrays with processed RNA isolated from purified Lgr5+ intestinal stem cells, secretory (Sec-Pro) and enterocyte (Ent-Pro) crypt progenitors, and mature villus enterocytes (ENT).
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| |
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| Contributor(s) |
Kim T, Li F, Ho L, Nalapareddy K, Shivdasani R |
| Citation(s) |
24413398 |
| |
| Submission date |
Oct 18, 2013 |
| Last update date |
May 04, 2018 |
| Contact name |
Fugen Li |
| E-mail(s) |
fugen_li@dfci.harvard.edu
|
| Organization name |
Dana-Farber Cancer Institute
|
| Street address |
450 Brookline Ave
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
|
| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE51464 |
An epigenetic basis for lateral inhibition and lineage plasticity in intestinal differentiation |
|
| Relations |
| BioProject |
PRJNA223240 |
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