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Status |
Public on Jun 01, 2017 |
Title |
CEBPA-mediated chromatin structure remodeling controls macrophage-specific differentiation and inflammatory gene expression program. |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Analysis of transcriptional regulation by CEBPA at gene expression level. The hypothesis tested in the present study was that CEBPA regulate genes involved in macrophage differentiation and function. Results provide important information of the transcriptome profiling of HEK293 cells expressing ectopic CEBPA, such as specific CEBPA-responsive genes, up- or down-regulated specific cellular functions.
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Overall design |
Total RNA obtained from uninfected HEK293 cells and compared to the HEK293 cells infected with the lentiviral vector containing CEBPA.
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Contributor(s) |
Chin KC, Zolezzi F, Poidinger M, Lum J |
Citation missing |
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Submission date |
Dec 11, 2013 |
Last update date |
Aug 13, 2018 |
Contact name |
Michael Poidinger |
E-mail(s) |
michael_poidinger@immunol.a-star.edu.sg
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Phone |
+6564070528
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URL |
http://www.sign.a-star.edu.sg
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Organization name |
Singapore Immunology Network
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Department |
Bioinformatics
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Street address |
#04-06, 8A Biomedical Grove
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City |
Singapore |
ZIP/Postal code |
138648 |
Country |
Singapore |
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Platforms (1) |
GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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Samples (6)
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Relations |
BioProject |
PRJNA231117 |